Rosuvastatin (Crestor) and Ketamine Therapy | Tovani Health
Crestor (Rosuvastatin) — HMG-CoA reductase inhibitor (statin)
Verdict at Tovani Health
Fully compatible; cleanest CYP profile of the statins.
Rosuvastatin and ketamine have no clinically significant interaction. Rosuvastatin is minimally CYP-metabolized (cleanest of the statins for drug interactions). Standard statin precautions apply but are independent of KAP.
If you take Crestor regularly and are considering at-home ketamine therapy, the combination is generally safe at therapeutic doses. This page covers the brief pharmacologic context and what we do at intake.
How Crestor interacts with ketamine
Rosuvastatin inhibits HMG-CoA reductase with minimal CYP involvement. No meaningful effect on ketamine pharmacology.
What we do at intake
Continue as normal.
Bottom line
Rosuvastatin and ketamine have no clinically significant interaction. Rosuvastatin is minimally CYP-metabolized (cleanest of the statins for drug interactions). Standard statin precautions apply but are independent of KAP.
Ready to find out if at-home ketamine fits your situation?
We’ll note that you’re on Crestor (Rosuvastatin) at intake. The eligibility check takes 5 minutes and gives you an honest answer about whether at-home ketamine fits your specific situation.
FL and NJ residents only. Benjamin Soffer, DO — Tovani Health.
Clinically reviewed
Reviewed by Benjamin Soffer, DO on May 17, 2026. Dr. Soffer is a board-certified physician (American Board of Internal Medicine) licensed in Florida and New Jersey, prescribing at-home ketamine therapy through Tovani Health.
This page is general information about how this medication interacts with at-home ketamine therapy at Tovani Health. It is not a substitute for medical advice from your prescribing physician about your specific situation. Always discuss medication changes with the doctor who prescribed them.