Dupilumab (Dupixent) and Ketamine Therapy | Tovani Health
Dupixent (Dupilumab) — IL-4Rα monoclonal antibody (atopic dermatitis, asthma, EoE, prurigo nodularis)
Verdict at Tovani Health
Fully compatible with KAP.
Dupilumab and ketamine have no clinically significant interaction. Same clean biologic-class profile. Used for atopic dermatitis, severe asthma, eosinophilic esophagitis, prurigo nodularis, and other type-2 inflammation conditions.
If you take Dupixent regularly and are considering at-home ketamine therapy, the combination is generally safe at therapeutic doses. This page covers the brief pharmacologic context and what we do at intake.
How Dupixent interacts with ketamine
Dupilumab is a fully human mAb blocking the IL-4 receptor alpha, neutralizing IL-4 and IL-13 signaling. Subcutaneous injection, usually every 2 weeks.
What we do at intake
Continue as scheduled.
Bottom line
Dupilumab and ketamine have no clinically significant interaction. Same clean biologic-class profile. Used for atopic dermatitis, severe asthma, eosinophilic esophagitis, prurigo nodularis, and other type-2 inflammation conditions.
Ready to find out if at-home ketamine fits your situation?
We’ll note that you’re on Dupixent (Dupilumab) at intake. The eligibility check takes 5 minutes and gives you an honest answer about whether at-home ketamine fits your specific situation.
FL and NJ residents only. Benjamin Soffer, DO — Tovani Health.
Clinically reviewed
Reviewed by Benjamin Soffer, DO on May 19, 2026. Dr. Soffer is a board-certified physician (American Board of Internal Medicine) licensed in Florida and New Jersey, prescribing at-home ketamine therapy through Tovani Health.
This page is general information about how this medication interacts with at-home ketamine therapy at Tovani Health. It is not a substitute for medical advice from your prescribing physician about your specific situation. Always discuss medication changes with the doctor who prescribed them.