Omega-3 (Fish Oil) and Ketamine Therapy | Tovani Health
Fish Oil (Omega-3 Fatty Acids) (also: Lovaza, Vascepa) — Polyunsaturated fatty acid supplement
Verdict at Tovani Health
Fully compatible with KAP.
Omega-3 fatty acids and ketamine have no clinically significant interaction. OTC fish oil and prescription preparations (Lovaza, Vascepa) are both fine to continue.
If you take Fish Oil regularly and are considering at-home ketamine therapy, the combination is generally safe at therapeutic doses. This page covers the brief pharmacologic context and what we do at intake.
How Fish Oil interacts with ketamine
EPA and DHA are anti-inflammatory polyunsaturated fatty acids with cardiovascular and possibly mood benefits. No CYP interactions of clinical significance.
What we do at intake
Continue as normal. Note that very high doses can mildly prolong bleeding time, which matters more for surgery than for KAP.
Bottom line
Omega-3 fatty acids and ketamine have no clinically significant interaction. OTC fish oil and prescription preparations (Lovaza, Vascepa) are both fine to continue.
Ready to find out if at-home ketamine fits your situation?
We’ll note that you’re on Fish Oil (Omega-3 Fatty Acids) at intake. The eligibility check takes 5 minutes and gives you an honest answer about whether at-home ketamine fits your specific situation.
FL and NJ residents only. Benjamin Soffer, DO — Tovani Health.
Clinically reviewed
Reviewed by Benjamin Soffer, DO on May 17, 2026. Dr. Soffer is a board-certified physician (American Board of Internal Medicine) licensed in Florida and New Jersey, prescribing at-home ketamine therapy through Tovani Health.
This page is general information about how this medication interacts with at-home ketamine therapy at Tovani Health. It is not a substitute for medical advice from your prescribing physician about your specific situation. Always discuss medication changes with the doctor who prescribed them.