Mupirocin (Bactroban) and Ketamine Therapy | Tovani Health
Bactroban (Mupirocin) (also: Centany) — Topical antibiotic (skin / nasal)
Verdict at Tovani Health
Fully compatible; topical delivery, minimal systemic absorption.
Mupirocin and ketamine have no clinically significant interaction. Topical ointment for impetigo, infected wounds, and nasal MRSA decolonization. Systemic absorption is essentially zero, so no drug-interaction concern at any dose.
If you take Bactroban regularly and are considering at-home ketamine therapy, the combination is generally safe at therapeutic doses. This page covers the brief pharmacologic context and what we do at intake.
How Bactroban interacts with ketamine
Mupirocin inhibits bacterial isoleucyl-tRNA synthetase. Used topically only. Minimal systemic absorption.
What we do at intake
Continue as prescribed.
Bottom line
Mupirocin and ketamine have no clinically significant interaction. Topical ointment for impetigo, infected wounds, and nasal MRSA decolonization. Systemic absorption is essentially zero, so no drug-interaction concern at any dose.
Ready to find out if at-home ketamine fits your situation?
We’ll note that you’re on Bactroban (Mupirocin) at intake. The eligibility check takes 5 minutes and gives you an honest answer about whether at-home ketamine fits your specific situation.
FL and NJ residents only. Benjamin Soffer, DO — Tovani Health.
Clinically reviewed
Reviewed by Benjamin Soffer, DO on May 22, 2026. Dr. Soffer is a board-certified physician (American Board of Internal Medicine) licensed in Florida and New Jersey, prescribing at-home ketamine therapy through Tovani Health.
This page is general information about how this medication interacts with at-home ketamine therapy at Tovani Health. It is not a substitute for medical advice from your prescribing physician about your specific situation. Always discuss medication changes with the doctor who prescribed them.