MCT Oil and Ketamine Therapy | Tovani Health
Brain Octane (MCT oil (medium-chain triglycerides)) (also: MCT C8 oil, Pure MCT) — Dietary fat supplement (ketogenic diet, mental clarity, energy)
Verdict at Tovani Health
Fully compatible with KAP.
MCT oil and ketamine have no clinically significant interaction. Common in ketogenic diets, bulletproof coffee, and as a quick energy source from rapidly-absorbed medium-chain fats. The intrinsic consideration is GI tolerance — starting too quickly causes nausea, cramping, and loose stools that can mimic side-effects of medications. Doesn't affect ketamine PK or PD.
If you take Brain Octane regularly and are considering at-home ketamine therapy, the combination is generally safe at therapeutic doses. This page covers the brief pharmacologic context and what we do at intake.
How Brain Octane interacts with ketamine
Medium-chain triglycerides (C6-C12 fatty acids, primarily caprylic C8 and capric C10) bypass standard fat absorption — directly into portal circulation rather than chylomicrons. Rapidly converted to ketone bodies. No CYP interaction with ketamine.
What we do at intake
Continue as you normally take it. Start low and slow if you're new (GI tolerance).
Bottom line
MCT oil and ketamine have no clinically significant interaction. Common in ketogenic diets, bulletproof coffee, and as a quick energy source from rapidly-absorbed medium-chain fats. The intrinsic consideration is GI tolerance — starting too quickly causes nausea, cramping, and loose stools that can mimic side-effects of medications. Doesn't affect ketamine PK or PD.
Ready to find out if at-home ketamine fits your situation?
We’ll note that you’re on Brain Octane (MCT oil (medium-chain triglycerides)) at intake. The eligibility check takes 5 minutes and gives you an honest answer about whether at-home ketamine fits your specific situation.
FL and NJ residents only. Benjamin Soffer, DO — Tovani Health.
Clinically reviewed
Reviewed by Benjamin Soffer, DO on May 23, 2026. Dr. Soffer is a board-certified physician (American Board of Internal Medicine) licensed in Florida and New Jersey, prescribing at-home ketamine therapy through Tovani Health.
This page is general information about how this medication interacts with at-home ketamine therapy at Tovani Health. It is not a substitute for medical advice from your prescribing physician about your specific situation. Always discuss medication changes with the doctor who prescribed them.