Lansoprazole (Prevacid) and Ketamine Therapy | Tovani Health
Prevacid (Lansoprazole) (also: Prevacid 24HR) — Proton pump inhibitor (PPI)
Verdict at Tovani Health
Fully compatible; same profile as omeprazole.
Lansoprazole and ketamine have no clinically significant interaction. Same PPI-class compatibility as omeprazole, pantoprazole, and esomeprazole. Available OTC.
If you take Prevacid regularly and are considering at-home ketamine therapy, the combination is generally safe at therapeutic doses. This page covers the brief pharmacologic context and what we do at intake.
How Prevacid interacts with ketamine
Lansoprazole inhibits gastric H+/K+ ATPase. CYP2C19 substrate. Minor effect on ketamine PK.
What we do at intake
Continue as normal.
Bottom line
Lansoprazole and ketamine have no clinically significant interaction. Same PPI-class compatibility as omeprazole, pantoprazole, and esomeprazole. Available OTC.
Ready to find out if at-home ketamine fits your situation?
We’ll note that you’re on Prevacid (Lansoprazole) at intake. The eligibility check takes 5 minutes and gives you an honest answer about whether at-home ketamine fits your specific situation.
FL and NJ residents only. Benjamin Soffer, DO — Tovani Health.
Clinically reviewed
Reviewed by Benjamin Soffer, DO on May 22, 2026. Dr. Soffer is a board-certified physician (American Board of Internal Medicine) licensed in Florida and New Jersey, prescribing at-home ketamine therapy through Tovani Health.
This page is general information about how this medication interacts with at-home ketamine therapy at Tovani Health. It is not a substitute for medical advice from your prescribing physician about your specific situation. Always discuss medication changes with the doctor who prescribed them.