Insulin and Ketamine Therapy | Tovani Health
Lantus (Insulin) (also: Humalog, Novolog, Tresiba, Toujeo, Levemir) — Hormone (diabetes management)
Verdict at Tovani Health
Compatible; the only consideration is monitoring blood sugar during the session.
Insulin and ketamine have no clinically significant interaction. The practical consideration: ketamine sessions involve fasting (typically 4-6 hours before), which changes the usual insulin dosing for the day. Patients on insulin work with us to plan the basal-bolus regimen around session timing.
If you take Lantus regularly and are considering at-home ketamine therapy, the combination is safe with monitoring or dose adjustment. This page covers the brief pharmacologic context and what we do at intake.
How Lantus interacts with ketamine
Insulin replaces or supplements endogenous insulin production. No direct ketamine PK interaction.
What we do at intake
Disclose all insulin types and doses. We coordinate session-day dosing with you: shorter basal doses may need adjustment to account for the fasting window, and bolus doses are skipped if meals are skipped.
Bottom line
Insulin and ketamine have no clinically significant interaction. The practical consideration: ketamine sessions involve fasting (typically 4-6 hours before), which changes the usual insulin dosing for the day. Patients on insulin work with us to plan the basal-bolus regimen around session timing.
Ready to find out if at-home ketamine fits your situation?
We’ll note that you’re on Lantus (Insulin) at intake. The eligibility check takes 5 minutes and gives you an honest answer about whether at-home ketamine fits your specific situation.
FL and NJ residents only. Benjamin Soffer, DO — Tovani Health.
Clinically reviewed
Reviewed by Benjamin Soffer, DO on May 17, 2026. Dr. Soffer is a board-certified physician (American Board of Internal Medicine) licensed in Florida and New Jersey, prescribing at-home ketamine therapy through Tovani Health.
This page is general information about how this medication interacts with at-home ketamine therapy at Tovani Health. It is not a substitute for medical advice from your prescribing physician about your specific situation. Always discuss medication changes with the doctor who prescribed them.