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Phenethylamine psychedelic (DEA Schedule I)Reviewed May 19, 2026

2C-B (Tucibí, Pink Cocaine) and Ketamine Therapy | Tovani Health

Tucibí (2C-B) (also: Tusi, Pink Cocaine)Phenethylamine psychedelic (DEA Schedule I)

Verdict at Tovani Health

Federally illegal; shorter-acting psychedelic but same framework as LSD.

2C-B is a DEA Schedule I controlled substance. Shorter duration than LSD (~4-6 hours active) and at lower doses can have more of a stimulant + mild psychedelic profile. The branded street product 'tusi' or 'pink cocaine' is frequently misidentified — laboratory analysis often shows ketamine, MDMA, or other mixtures rather than actual 2C-B. We do not run ketamine sessions in proximity to 2C-B use. The mixing-up-with-other-drugs problem makes recent disclosure especially important.

If you take Tucibí regularly and are considering at-home ketamine therapy, the combination is depends on your specific situation. This page covers the brief pharmacologic context and what we do at intake.

How Tucibí interacts with ketamine

2C-B agonizes 5-HT2A and 5-HT2C receptors. Shorter duration than LSD. The 'pink cocaine' street name causes real confusion — analytical testing in multiple jurisdictions has shown these products often contain ketamine, MDMA, or both, not actual 2C-B.

What we do at intake

Disclose any recent use, including products sold as 'tusi' or 'pink cocaine' since those may actually be MDMA + ketamine. We ask for at least 2 weeks of abstinence given the contamination risk.

Bottom line

2C-B is a DEA Schedule I controlled substance. Shorter duration than LSD (~4-6 hours active) and at lower doses can have more of a stimulant + mild psychedelic profile. The branded street product 'tusi' or 'pink cocaine' is frequently misidentified — laboratory analysis often shows ketamine, MDMA, or other mixtures rather than actual 2C-B. We do not run ketamine sessions in proximity to 2C-B use. The mixing-up-with-other-drugs problem makes recent disclosure especially important.

Ready to find out if at-home ketamine fits your situation?

We’ll note that you’re on Tucibí (2C-B) at intake. The eligibility check takes 5 minutes and gives you an honest answer about whether at-home ketamine fits your specific situation.

FL and NJ residents only. Benjamin Soffer, DO — Tovani Health.

Sources

The verdict and clinical guidance on this page are based on the following peer-reviewed literature and FDA prescribing information.

  1. Psychedelics. Nichols DE. Pharmacological Reviews. 2016. PMID: 26841800

Clinically reviewed

Reviewed by Benjamin Soffer, DO on May 19, 2026. Dr. Soffer is a board-certified physician (American Board of Internal Medicine) licensed in Florida and New Jersey, prescribing at-home ketamine therapy through Tovani Health.

This page is general information about how this medication interacts with at-home ketamine therapy at Tovani Health. It is not a substitute for medical advice from your prescribing physician about your specific situation. Always discuss medication changes with the doctor who prescribed them.