2C-B With Ketamine: Proceed With Care
Tucibí (2C-B) (also: Tusi, Pink Cocaine) — Phenethylamine psychedelic (DEA Schedule I)
Verdict at Tovani Health
Federally illegal; shorter-acting psychedelic but same framework as LSD.
2C-B is a DEA Schedule I controlled substance. Shorter duration than LSD (~4-6 hours active) and at lower doses can have more of a stimulant + mild psychedelic profile. The branded street product 'tusi' or 'pink cocaine' is frequently misidentified — laboratory analysis often shows ketamine, MDMA, or other mixtures rather than actual 2C-B. We do not run ketamine sessions in proximity to 2C-B use. The mixing-up-with-other-drugs problem makes recent disclosure especially important.
If you take Tucibí regularly and are considering at-home ketamine therapy, eligibility depends on your specific situation. We evaluate case by case. This page covers the brief pharmacologic context and what we do at intake.
How Tucibí interacts with ketamine
2C-B agonizes 5-HT2A and 5-HT2C receptors. Shorter duration than LSD. The 'pink cocaine' street name causes real confusion — analytical testing in multiple jurisdictions has shown these products often contain ketamine, MDMA, or both, not actual 2C-B.
What we do at intake
Disclose any recent use, including products sold as 'tusi' or 'pink cocaine' since those may actually be MDMA + ketamine. We ask for at least 2 weeks of abstinence given the contamination risk.
Bottom line
2C-B is a DEA Schedule I controlled substance. Shorter duration than LSD (~4-6 hours active) and at lower doses can have more of a stimulant + mild psychedelic profile. The branded street product 'tusi' or 'pink cocaine' is frequently misidentified — laboratory analysis often shows ketamine, MDMA, or other mixtures rather than actual 2C-B. We do not run ketamine sessions in proximity to 2C-B use. The mixing-up-with-other-drugs problem makes recent disclosure especially important.
Ready to find out if at-home ketamine fits your situation?
We’ll note that you’re on Tucibí (2C-B) at intake. The eligibility check takes 5 minutes and gives you an honest answer about whether at-home ketamine therapy fits your specific situation, and if it does, a licensed physician can write your online ketamine prescription without an in-person visit.
FL, NJ & CA residents only. Benjamin Soffer, DO: Tovani Health.
Sources
The verdict and clinical guidance on this page are based on the following peer-reviewed literature and FDA prescribing information.
- Psychedelics. Nichols DE. Pharmacological Reviews. 2016. PMID: 26841800
Clinically reviewed
Reviewed by Benjamin Soffer, DO on May 19, 2026. Dr. Soffer is a board-certified physician (American Board of Internal Medicine) licensed in Florida, New Jersey, and California, prescribing at-home ketamine therapy through Tovani Health.
This page is general information about how this medication interacts with at-home ketamine therapy at Tovani Health. It is not a substitute for medical advice from your prescribing physician about your specific situation. Always discuss medication changes with the doctor who prescribed them.