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How to Talk to Your Therapist About Ketamine Therapy

Dr. Ben Soffer
May 08, 2025
7 min read

How to Talk to Your Therapist About Ketamine Therapy

You have done your research. You have read about how ketamine works for depression, anxiety, and PTSD. You think it might help. But now comes a conversation that many patients tell me feels harder than it should: bringing it up with your current therapist or prescriber.

I understand the hesitation. You might worry about being judged, dismissed, or told you are "doctor shopping." You might not know how to explain what you have learned without sounding like you got your medical degree from the internet. And if your provider is not familiar with ketamine therapy, the conversation can feel like an uphill climb.

Here is how to navigate it with confidence.

Why This Conversation Matters

Before we get into the how, let me address the why. You might be wondering whether you even need to tell your therapist or psychiatrist about ketamine therapy, especially if you plan to pursue it through a separate provider like Tovani Health.

The answer is yes, and here is why:

Coordinated care leads to better outcomes. Your therapist understands your psychological history, your patterns, your triggers. When they know you are doing ketamine therapy, they can adjust their approach to help you integrate the insights and shifts that often emerge during treatment.

Medication safety. If you have a psychiatrist prescribing other medications, they need to know about ketamine to watch for interactions and coordinate any adjustments to your existing regimen.

Your therapeutic relationship deserves honesty. Hiding a major treatment decision from your provider creates a disconnect in the therapeutic relationship. Being open about what you are considering -- even if the conversation feels uncomfortable -- is an act of self-advocacy.

Preparing for the Conversation

A little preparation goes a long way. Here is how to set yourself up for a productive discussion.

Know Your "Why"

Before the appointment, get clear on why you are considering ketamine therapy. Your reasoning will carry more weight if it is grounded in your own experience, not just general information. Think about:

  • What you have already tried and how it went. "I have been on three different SSRIs over the past two years, and the best result I got was marginal improvement with significant side effects."
  • What is not working about your current treatment. "I am doing the work in therapy, but the depression is so heavy that I cannot access the tools we discuss in session."
  • Why ketamine specifically. "I have read that ketamine works through a different mechanism than SSRIs, and I am interested in exploring it because the serotonin-based approach has not been effective for me."

Gather a Few Key Facts

You do not need to deliver a medical lecture, but having a few facts at your fingertips helps:

  • Ketamine has been used safely in medicine for over 50 years, primarily as an anesthetic
  • It works through the glutamate/NMDA system, not the serotonin system that SSRIs target
  • The FDA approved esketamine (Spravato) for treatment-resistant depression in 2019, validating the ketamine mechanism
  • Racemic ketamine (the form used in at-home therapy) has extensive clinical evidence supporting its use for depression
  • At-home sublingual ketamine therapy is legal, prescribed by licensed physicians, and supervised with ongoing clinical monitoring

For a deeper understanding you can share, point them to our how ketamine works page.

Choose the Right Moment

Do not spring this on your therapist in the last five minutes of a session. If possible, let them know in advance that you would like to discuss a treatment option you have been researching. You might say: "I would like to use some of our time next session to talk about something I have been looking into for my depression." This gives them a chance to be prepared and allocate time for a real conversation.

Talking Points That Work

Here are specific ways to frame the conversation that I have seen work well for patients:

Lead with Your Experience, Not the Treatment

Instead of: "I want to try ketamine therapy."

Try: "I have been thinking a lot about where I am with treatment. I have been on [medication name] for [duration], and while I appreciate the stability it provides, I am still struggling significantly with [specific symptoms]. I have been researching other options and want to talk about ketamine therapy."

Leading with your experience makes it a collaborative discussion rather than a request for a specific prescription.

Acknowledge Their Expertise

Try: "I know you have a much better understanding of my clinical picture than I do. I wanted to bring this to you so we can discuss whether it makes sense for my situation."

This frames you as a partner in your care, not someone bypassing their judgment.

Address the Elephant in the Room

If you sense hesitation about the word "ketamine," address it directly:

Try: "I know ketamine has a complicated reputation because of recreational misuse. But what I am looking at is supervised, low-dose therapy prescribed by a physician specifically for treatment-resistant depression. It is a very different context."

Be Honest About Where You Found the Information

Try: "I have been reading clinical literature and looking at providers who specialize in this. I am not asking you to prescribe it -- I am asking for your perspective on whether this could be a reasonable next step given my treatment history."

If Your Therapist Is Supportive

Some therapists will be immediately receptive. If so, here is how to make the most of that support:

  • Ask them to be part of your care team. Let them know you would like to continue therapy alongside ketamine treatment, and ask if they would be open to coordinating with your ketamine prescriber.
  • Discuss integration. Ketamine often opens emotional windows that can be incredibly productive in therapy. Ask your therapist if they are familiar with integration work, or if they would be willing to learn about it.
  • Set up a communication plan. With your consent, your therapist and your ketamine physician can share relevant clinical notes. At Tovani Health, we welcome collaboration with our patients' existing providers.

If Your Therapist Is Skeptical

Not all providers are up to date on ketamine research, and some carry outdated assumptions. Here is how to handle common objections:

"There is not enough research."

Your response: "I understand the concern. The research on ketamine for depression actually goes back over 20 years, starting with the landmark NIH study in 2000. There have been numerous randomized controlled trials since then, and the FDA's approval of esketamine in 2019 was based on substantial clinical evidence. I am happy to share some of the published studies if that would be helpful."

"It is just a recreational drug."

Your response: "Ketamine has been on the WHO's List of Essential Medicines for decades because of its safety profile as an anesthetic. At therapeutic doses for depression -- which are much lower than anesthetic doses -- it works through specific neurological mechanisms. The recreational use and the medical use are very different things."

"You should try another antidepressant first."

Your response: "I hear you, and I appreciate you wanting to be thorough. I have already tried [list medications and durations]. At what point would you consider a different mechanism of action worth exploring? The clinical literature defines treatment-resistant depression as failing two or more adequate antidepressant trials, and I have met that threshold."

"I do not know enough about it to feel comfortable."

Your response: "I respect that honesty. Would you be open to reviewing some of the research? I can also provide information about the provider I am considering -- they are board-certified physicians who specialize in this, and they would be happy to discuss their protocols with you."

If Your Provider Is Firmly Opposed

Sometimes, despite your best efforts, a therapist or psychiatrist is simply not open to the conversation. If this happens:

Respect their position, but advocate for yourself. You can say: "I appreciate your perspective, and I understand your concerns. I would still like to explore this option with a provider who specializes in ketamine therapy, and I hope we can continue working together regardless."

You do not need your therapist's permission. While coordination is ideal, you have every right to seek additional medical opinions and pursue treatments that you believe are in your best interest. Ketamine therapy through a practice like Tovani Health is a separate medical relationship, just as seeing a cardiologist would be separate from your relationship with your therapist.

Consider whether this is a red flag. A provider who dismisses a well-researched, evidence-based treatment without engaging with the evidence may not be the right fit for your ongoing care. A good therapeutic relationship includes room for respectful disagreement and collaborative decision-making.

Know that you have options. You can pursue ketamine therapy through Tovani Health independently. Our eligibility screening is free and confidential, and our physicians will conduct their own comprehensive evaluation.

What to Tell Your Therapist About Tovani Health Specifically

If the conversation turns to which provider you are considering, here is what you can share:

  • Tovani Health is a physician-led practice -- evaluations and prescribing are done by board-certified physicians, not mid-level providers
  • Every patient receives a comprehensive medical evaluation via video consultation before any prescription is written
  • Treatment includes ongoing monitoring and follow-up, not just a one-time prescription
  • We work with licensed, DEA-registered compounding pharmacies
  • We welcome coordination with existing providers and can share treatment notes with your consent
  • We serve patients in Florida and New Jersey
  • Our safety protocols are rigorous and transparent

A Note About Self-Advocacy

I want to acknowledge something: having to advocate for your own treatment should not be this hard. In an ideal world, every mental health provider would be current on the evidence for ketamine therapy and proactively discuss it with patients who have not responded to conventional treatments.

We are not in that ideal world yet. But the landscape is shifting. More providers are becoming informed. More patients are asking the right questions. And treatments that were considered fringe five years ago are increasingly recognized as mainstream options.

You are not being difficult by bringing this up. You are being an informed, engaged participant in your own healthcare. That is exactly what good medicine looks like.

The Conversation You Do Not Need to Have First

One final thought: while talking to your therapist is valuable, it is not a prerequisite. If you are considering ketamine therapy and want to learn whether you are a candidate, you can start with us directly. Our physicians will assess your full clinical picture, including your current treatments and providers, and we will recommend coordination where appropriate.


Ready to take the next step? Check your eligibility for ketamine therapy -- it is free, confidential, and takes less than 5 minutes. Whether you have already talked to your therapist or are still working up to it, we are here to answer your questions and help you make an informed decision.

About the Author

Dr. Ben Soffer is a board-certified physician specializing in ketamine therapy for treatment-resistant depression and anxiety disorders. Based in Florida and New Jersey, Dr. Soffer provides evidence-based, physician-supervised ketamine treatment through Tovani Health.