
Patient Experience
My First Week with At-Home Ketamine: What Nobody Tells You
Dr. Ben Soffer
April 02, 2026
8 min read
# My First Week with At-Home Ketamine: What Nobody Tells You
Starting ketamine therapy at home felt both exciting and nerve-wracking. After years of trying traditional antidepressants with limited success, I was ready for something different – but nothing quite prepares you for those first few days.
## Day 1: The Setup Anxiety
The medication arrived discreetly (as promised), and I spent an hour just staring at the package. The instructions were clear, but my mind was racing: *What if this doesn't work? What if I feel weird? What if my family notices?*
**Pro tip**: Set up your "treatment space" beforehand. I created a cozy corner with soft pillows, my favorite playlist, and dim lighting. Having everything ready reduced my pre-treatment jitters.
## Days 2-3: The "Floating" Feeling
The dissociative effects were gentler than I expected. Rather than feeling completely disconnected, it was more like watching my thoughts from a comfortable distance. I finally understood why they call it "floating."
**What helped**:
- Having a trusted friend on standby (even just knowing they were available)
- Keeping a journal nearby to jot down insights
- Not fighting the experience – just letting it happen
## Days 4-5: The Subtle Shifts
This is when I noticed the first real changes. Not dramatic, but meaningful:
- Waking up felt less heavy
- I caught myself humming while making coffee
- Negative thought loops seemed... quieter
## Days 6-7: Integration Time
The treatment days were profound, but the "integration" days between sessions proved equally important. I started noticing patterns in my journal – themes of self-compassion emerging, old memories feeling less charged.
## What Nobody Mentions
**The logistics matter**: I learned to eat something light beforehand (but not too much), clear my schedule for 3-4 hours, and have easy-to-digest snacks ready.
**Your support system is crucial**: Even though you're home alone during treatment, having people who understand what you're doing makes a huge difference.
**It's not instant magic**: The first week is just the beginning. Real healing happens in the spaces between treatments, in how you start relating to yourself differently.
## Week 2 Preview
As I write this, preparing for my second week, I feel something I haven't felt in years: genuine curiosity about my own healing process. Not desperate hope, not skeptical doubt – just open, patient curiosity.
If you're considering at-home ketamine therapy, know that it's okay to feel nervous. That nervousness might just be your intuition telling you you're on the verge of something important.
*Ready to start your own healing journey? Check your eligibility for at-home ketamine therapy today.*
About the Author
Dr. Ben Soffer is a board-certified physician specializing in ketamine therapy for treatment-resistant depression and anxiety disorders. Based in Florida and New Jersey, Dr. Soffer provides evidence-based, physician-supervised ketamine treatment through Tovani Health.